MEDICAL ISOTOPES ARE USED DAILY around the world to visualise and diagnose cancer, heart disease and other serious ailments. However, the production of these medical isotopes can emit gases that, while posing no danger to the public, have features that look similar to those produced by a nuclear explosion.

The US Department of Energy’s Pacific Northwest National Laboratory (PNNL) is working with production facilities around the world to install monitors that will help understand more about the levels and timing of these emissions. Using that information, governments and agencies watching for signatures of nuclear explosions can more easily assess their readings and ensure emissions from medical isotope production are not misinterpreted.

First-of-a-kind

In October 2018, PNNL worked with the Australian Nuclear Science and Technology Organisation (ANSTO) to install a detector system at ANSTO’s medical isotope production facility in Lucas Heights, south of Sydney in Australia. Previously, the Institute for Radioelements (IRE) in Fleurus, Belgium installed a monitor in its effluent stack. Both IRE and ANSTO produce the medical isotope molybdenum‐99 (Mo‐99) by irradiating uranium in a reactor. Gaseous fission products, including isotopes of xenon, are released in the process, increasing worldwide background levels of this gas.

“These first‐of‐their-kind sensor systems, one in each hemisphere, will help with international measurements for detecting underground nuclear explosions,” said Judah Friese, principal investigator at PNNL. “While these are the first companies to install these systems, more installations are planned at locations around the globe to increase confidence in international nuclear explosion monitoring.”

The Preparatory Commission for the Comprehensive Nuclear‐Test‐Ban Treaty Organization notes that four radioxenon isotopes are possible indicators of a nuclear explosion, and may provide forensic evidence for analysts. (These isotopes are Xe‐133, Xe‐133m, Xe‐131m, and Xe‐135). CTBTO PrepCom analysts track airborne radioxenon through the International Monitoring System (IMS).

PNNL scientists are experts in developing methods of detecting extremely low levels of radioactive isotopes. While the monitors being installed in the stacks are off‐the‐shelf devices, they’ve been slightly modified to PNNL specifications.

“It’s important to understand the levels and timing of xenon released by medical isotope facilities the world over, which is significant but relatively uncharted until now,” said Friese. “Stack release data will support the job of analysts monitoring the globe for nuclear explosions.”

Additional detectors

PNNL is working with the US Departments of State and Defense and the National Nuclear Security Administration (NNSA) to install additional detectors via a project called STAX, or Source Term Analysis of xenon.

There are currently no companies in the USA that produce molybdenum‐99 through the fission of uranium. However, approximately 40,000 Americans receive doses of Technetium‐99m each day, typically to diagnose cancer, heart disease and other serious health conditions. Technetium‐99m is a short‐lived daughter radioisotope of Mo‐99. Worldwide, there are some 40 million procedures done per year involving Technetium‐99m, most of which is derived from fission‐based Mo‐99 that gives off radioxenon during its production process.

The network of stack monitors will confidentially transmit data to a central database for compilation, analysis, and screening. Eventually, the data created by these stack monitors will be used in a model that predicts xenon levels in the atmosphere. In the event of a suspected nuclear explosion, this knowledge can quickly rule out unrelated sources of xenon.  


Information provided by Pacific Northwest National Laboratory